1. In 1980, Ganoderma lucidum was firstly found to have anti-radiation damage in mainland China. Gavage of ganoderma lucidum liquid (10g/kg) to mice for 20d before 60Coγ ray irradiation, and continue to give the drug for 2 weeks after irradiation, could significantly reduce the mortality of the animals. The mortality rates of Ganoderma lucidum group and control group 30d after irradiation were 44.4% and 70.4%, respectively. After 60Coγ-ray irradiation, the intraperitoneal injection of Ganoderma lucidum liquid (10g/kg) into mice had no effect on the mortality rate of 30d after irradiation, but it could prolong the average survival time of the dead animals significantly.
2、Taiwanese scholars Hsu et al. (1990) also proved that intraperitoneal injection of Ganoderma lucidum extract has certain protective effects on the damage caused by X-ray irradiation in mice, which can mildly increase the survival rate of 30d after irradiation, and promote the recovery of body weight and blood image of mice after irradiation.
3、Yu Suqing et al. (1997) found that gavage of Ganoderma lucidum spore powder 1g/kg and 2g/kg to mice had an inhibitory effect on leukopenia induced by 60Coγ rays and increased the survival rate of mice.
4. The protective effect of Ganoderma lucidum on radioactive injury may be related to its stimulation of bone marrow hematopoietic function. The study of Guan Hongchang et al. (1981) confirmed that daily intraperitoneal injection of Ganoderma lucidum polysaccharide D6 (74mg/kg) into mice could increase the participation of 3H-leucine, 3H-thymine nucleoside and 3H-uracil nucleoside in bone marrow cell proteins, DNA and RNA, respectively, by 28.5%, 43.3% and 45.7% compared with that in the control group after 7d, which indicated that Ganoderma lucidum polysaccharide could promote the participation of This indicates that Ganoderma lucidum polysaccharides can promote the synthesis of protein and nucleic acid in bone marrow cells and accelerate the division and proliferation of bone marrow cells.
7. Wang Danhua et al. (2006) studied the inhibitory effect of Ganoderma lucidum extracts on tumor cells and proved that Ganoderma lucidum extracts could reduce radiation damage, had obvious anti-tumor effects in vitro and had a protective effect on the damage to normal human cells induced by radiation and chemotherapeutic drug cisplatin.
#Protective effects of Ganoderma lucidum on radiation damage #anti-nuclare radiation damage